Comparison Between Two Noninvasive Methods Used to Estimate Biomechanical Properties of the Internal Carotid Artery

Background: Many cardiovascular diseases modified the arterial wall stiffness. Objectives: This work focuses on the quantification of the elastic biomechanical properties of the internal carotid (ICA) wall by applying the cepstral analysis on healthy volunteers aged from 22 to 86 years old. The purpose of this study is to compare two methods of measurement of arterial compliance ([Formula: see text], arterial distensibility ([Formula: see text], arterial elastance (Eh), and Young’s modulus ([Formula: see text]. Material and methods: First, arterial compliance and arterial distensibility were measured in function of wave speed ([Formula: see text], which is measured in our previous works by using two methods. Second, elastance Eh was estimated through the ratio between diastolic radius ([Formula: see text] and [Formula: see text]. Finally, [Formula: see text] was estimated from a statistical study from the literature on h due to the difficulty of measuring wall thickness ([Formula: see text]. Results: The Student test demonstrated that there is a very significant difference between young and old subjects in terms of elastance, compliance, and Young’s modulus ([Formula: see text]). These findings are in agreement with the reference values reported in the literature. They are very satisfying for distinguishing a pathological change in parietal elasticity. Conclusion: The in vivo application of these methods presents their potential for clinical measurement of arterial stiffness.