Why the study?
Do antipsychotic medications increase the risk of sudden cardiac death in psychiatric patients?
Do antipsychotic medications increase the risk of sudden cardiac death in psychiatric patients?
This review highlights the cardiotoxic effects of antipsychotic medications, specifically QT prolongation and sudden cardiac death, emphasizing the importance of risk factor identification and prevention in psychiatric patients.
Antipsychotics may raise SCD risk via QT effects in psychiatric patients; leaves open optimal monitoring and prevention strategies.
The review summarises the evidence from international publications on sudden cardiac death (SCD) in psychiatric patients receiving neuroleptics. Modern SCD definitions are presented, together with the relevant epidemiological data. The pathogenesis of fatal cardiac arrhythmias, caused by cardiotoxic effects of antipsychotic medications, is discussed. Electrocardiographic changes, in particular QT interval changes, as well as risk factors of SCD and main principles of its prevention, are described in detail.
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В. П. Волков (2012) studied this question.
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