Interacting TCP and NLP transcription factors control plant responses to nitrate availability

Significance Nitrate is an essential nutrient and a critical signal for plant growth, development, and stress responses. Nitrate signaling underlies a myriad of physiological, morphological, and developmental processes. Here we report that interacting teosinte branched1/cycloidea/proliferating cell factor and NIN-like protein transcription factors constitute a molecular link between nitrate signaling and the control of the cell-cycle progression gene CYCB1;1 and root meristem growth. Our findings shed light on the regulatory mechanisms underlying an important plant adaptive process for coping with and surviving environmental challenges.