Population
85 rat ventricular myocyte monolayers (44 infected with I adenovirus, 41 littermate controls infected with…
Comparison
Infection with an adenovirus carrying the… vs Infection with a GFP adenovirus
Design
Preclinical
Authors
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May promote wavebreaks in reentry models; hypothesis-generating for tachyarrhythmia mechanisms and requires in vivo validation.
Adenoviral expression of I(Ks) in rat cardiomyocyte monolayers promotes wavebreak formation and fibrillatory conduction, highlighting its potential role in tachyarrhythmias.
Muñoz et al. (2007) studied this question.
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