Why the study?
Does percutaneous balloon mitral valvuloplasty improve left atrial appendage function in patients with symptomatic rheumatic mitral stenosis?
Does percutaneous balloon mitral valvuloplasty improve left atrial appendage function in patients with symptomatic rheumatic mitral stenosis?
Percutaneous balloon mitral valvuloplasty significantly improves left atrial appendage function and reduces spontaneous echo contrast, potentially lowering future thromboembolic risk.
PBMV was associated with improved LAA function in rheumatic MS; hypothesis-generating for thromboembolic risk reduction, needs prospective confirmation.
BACKGROUND: To compare left atrial appendage (LAA) function by Doppler and Doppler tissue imaging (DTI) before and after percutaneous balloon mitral valvuloplasty (PBMV). MATERIALS AND METHODS: Fifty-nine patients with symptomatic rheumatic mitral stenosis who underwent PBMV were included in this study. LAA function was measured before and after PBMV. To study LAA function, LAA late emptying (LAALE) velocity, LAA late filling (LAALF) velocity, and LAA area change percentage (LAAAC %) were measured. In the DTI study, tissue Doppler velocities of the LAA, including peak early diastolic (E(LAA)), peak late diastolic (A(LAA)), and peak systolic (S(LAA)), were measured. RESULTS: There was significant increase in LAALE velocity, LAALF velocity, E(LAA), A(LAA), S(LAA) waves measured by Doppler and DTI after PBMV compared with baseline (p < 0.001) but there was no significant change in LAAAC% (p = not significant). Spontaneous echo contrast was present in 10 of the 59 patients before the procedure. It completely disappeared (6 patients) or decreased (4 patients) after PBMV. CONCLUSIONS: Our results suggest that PBMV improves LAA function and, thereby, may have a favorable influence on future thromboembolic complications.
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Reddy et al. (2012) studied this question.
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