Population
In vitro model of actin and myosin
Comparison
Addition of actin to myosin in a 1:4 ratio in… vs Addition of actin to myosin in the presence of…
Design
Preclinical
Authors
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Should not yet influence clinical decisions; leaves open physiological relevance of actomyosin regulation in cardiac muscle.
The study demonstrates that actin can inhibit myosin ATPase activity in the absence of magnesium, suggesting a conformational change in the active site.
Barron et al. (1966) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: