Synthesis and Anti-Inflammatory Activity of Some -5-Ethoxy-2- Mercapto Benzimidazole Derivatives

This article includes a description of new series of 5-ethoxy-2-mercapto benzimidazole derivatives, synthesized and evaluated for the anti-inflammatory activity; the synthesis involved the reaction of the parent nucleus (5-ethoxy-2- mercapto benzimidazole) with different p-phenacyl bromide substituents. All the newly synthesized compounds were screened for their anti-inflammatory activity by egg albumin-induced rat hind paw edema method.