Why the study?
The direct relationship between arterial blood flow and micro-perfusion remains controversial within the foot angiosome concept used in vascular surgery.
Diffuse speckle contrast analysis is a feasible modality for monitoring tissue perfusion and assessing low frequency oscillations in the foot angiosome.
DSCA LFO correlations on healthy feet did not align with angiosome boundaries; leaves open clinical relevance in CLI.
An angiosome refers to a 3D tissue volume that is vascularized by a single artery and is a relatively new concept that is useful in vascular surgery; however, the direct relationship between arterial blood flow and micro-perfusion is still controversial. Here, we propose a diffuse speckle contrast analysis (DSCA), which is an emerging tissue perfusion monitoring modality, to investigate the correlations among low frequency oscillations (LFOs) measured from different areas on the feet of healthy subjects. We obtained reproducible results from the correlation analyses of LFOs, and their physiological implications were discussed. In order to confirm the changes in the frequency oscillations, we analyzed and compared the power spectral density changes due to heart rate variability in the electrocardiographic signal during reactive hyperemia and head-up tilt protocols.
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Yeo et al. (2020) studied this question.
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