Why the study?
What patient factors and documentation practices are associated with withholding versus withdrawing acute hemodialysis in seriously ill hospitalized patients with renal failure?
What patient factors and documentation practices are associated with withholding versus withdrawing acute hemodialysis in seriously ill hospitalized patients with renal failure?
Older age, male gender, and cancer diagnosis predict withholding rather than withdrawing dialysis in seriously ill patients, with withholding decisions being less frequently documented.
Alerts clinicians to possible decision biases in seriously ill patients; leaves open whether targeted documentation improves equity.
OBJECTIVE: We evaluated prospectively the use of acute hemodialysis among hospitalized patients to identify demographic and clinical predictors of and chart documentation concerning dialysis withheld and withdrawn. DESIGN: Prospective cohort study. SETTING: Five teaching hospitals. PATIENTS: Five hundred sixty-five seriously ill hospitalized patients who had not previously undergone dialysis who developed renal failure. MAIN OUTCOME MEASURES: Patient demographics, clinical characteristics, preferences, and prognostic estimates associated with having dialysis withheld rather than initiated and withdrawn rather than continued. Differences in chart documentation concerning decision-making for dialysis withheld, withdrawn, and continued. RESULTS: Older patient age, cancer diagnosis, and male gender were associated with dialysis withheld rather than withdrawn. Age and gender differences persisted after adjustment for patients' aggressiveness of care preference. Worse 2-month prognosis was associated with both withholding and withdrawing dialysis. Chart documentation of decision-making was lacking more often for patients with dialysis withheld than for dialysis withdrawn. CONCLUSIONS: Measuring the equity of life-sustaining treatment use will require evaluation of care withheld, not just care withdrawn. Older patients and men, after accounting for prognosis and function, are more likely to have dialysis withheld than withdrawn after a trial. Further exploration is needed into this disparity and the inadequate chart documentation for patients with dialysis withheld.
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Wenger et al. (2000) studied this question.
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