Population
HeLa cells infected with Coxsackievirus B3 (CVB3)
Comparison
Inhibition of caspase activation by… vs Control apoptotic cells induced by treatment…
Design
Preclinical
Follow-up
9 hours following infection
Authors
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Caspase inhibition fails to block CVB3 cytopathic effects in HeLa cells; leaves open caspase-independent death pathways in viral myocarditis models.
Caspase activation is not responsible for the primary cytopathic effect of Coxsackievirus B3 infection in HeLa cells, though it occurs as a late-stage event.
Carthy et al. (1998) studied this question.
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