September 11, 2019Journal of Magnetic Resonance Imaging

Normal myocardial native T1 values in children using single‐point saturation recovery and modified look–locker inversion recovery (MOLLI)

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Why the study?

Normal pediatric myocardial T1 values are scarce using MOLLI sequences and unavailable using Smart1Map, a single-point saturation recovery sequence that measures true T1.

Does Smart1Map yield different normal myocardial T1 values compared to MOLLI in healthy children?

Comparison

Smart1Map vs MOLLI T1 mapping at 1.5T

Design

Prospective cohort study

Authors

BBBarbara BurkhardtUniversity Children's Hospital Zurich CMCristina MenghiniJohn Brown University BRBeate RückerUniversity Children's Hospital Zurich

Discussion

Member takes

Implication

Provides pediatric Smart1Map T1 norms; extends MOLLI data but leaves open disease validation before clinical use.

Structured PICO

Does Smart1Map yield different normal myocardial T1 values compared to MOLLI in healthy children?

Population

34 children and adolescents aged 8–18 years (14 males) without cardiovascular or inflammatory diseases.

Intervention

Smart1Map (single-point saturation recovery sequence) at 1.5T

Comparator

MOLLI (modified Look-Locker inversion recovery) at 1.5T

Outcome

Mean T1 values of the left ventricular myocardium, the interventricular septum, and the blood pool in basal, mid-ventricular, and apical short axis slicessurrogate

Smart1Map yields significantly longer normal myocardial T1 values compared to MOLLI in healthy children, establishing reference values for this sequence.

Cite This Study

Burkhardt et al. (2019) studied this question.

synapsesocial.com/papers/6a72dcd193a4d5cf641ae721 https://doi.org/10.1002/jmri.26910

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Normal myocardial native T1 values in children using single‐point saturation recovery and modified look–locker inversion recovery (MOLLI)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Normal myocardial native T1 values in children using single‐point saturation recovery and modified look–locker inversion recovery (MOLLI)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider