October 1, 1970CirculationOpen Access

Hemodynamic Determinants of Exercise ST-Segment Depression in Coronary Patients

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Population

8 patients with coronary heart disease

Design

Case_series

Authors

JDJean-Marie R. DetryCardiac Imaging FPFRANZ PIETTEUCLouvain LBLucien A. BrasseurCliniques Universitaires Saint-Luc

Discussion

Member takes

Implication

Caution against comparing ECG changes without matching myocardial work; leaves open validation in prospective cohorts.

Structured PICO

Population

8 patients with coronary heart disease

Intervention

Two periods of exercise separated by 30 min of rest, with workload increased in a stepwise fashion every minute up to limiting symptoms

Outcome

Relationship between magnitude of exercise ST-segment depression and indices expressing myocardial oxygen requirements (pressure-time index)surrogate

Exercise-induced ST-segment depression correlates closely with myocardial oxygen demand, suggesting that therapeutic efficacy assessed by ECG must be compared at equivalent levels of myocardial work.

Cite This Study

Detry et al. (1970) studied this question.

synapsesocial.com/papers/6a72dd0bd8e6791e25543c06 https://doi.org/10.1161/01.cir.42.4.593

View Full Paper

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Bookmark

Hemodynamic Determinants of Exercise ST-Segment Depression in Coronary Patients

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Hemodynamic Determinants of Exercise ST-Segment Depression in Coronary Patients

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider