Why the study?
Does P-wave duration during exercise differ between patients with coronary artery disease and normal subjects?
Does P-wave duration during exercise differ between patients with coronary artery disease and normal subjects?
P-wave prolongation during exercise occurs earlier in CAD patients and may reflect increased left-ventricular end-diastolic pressure, potentially preceding ST-segment depression.
May precede ST depression in CAD; cross-sectional data leaves open diagnostic utility in exercise testing.
The exercise-induced increase in P-wave duration reported previously has not been studied on a minute-by-minute basis. We measured the P duration in 47 normal subjects and 43 coronary artery disease (CAD) patients each minute during an exercise test. We found that prolongation of the P wave in those with CAD occurs relatively early and the difference between normal subjects and CAD patients is greater near maximum exercise. The data suggest that an increase in P-wave duration may reflect an increase in the left-ventricular end-diastolic pressure and may occur earlier that ST-segment depression.
No takes yet. Share an insight, caveat, or question.
Pandya et al. (2008) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: