Po-26 Bilateral Symmetry of Brachial Pulse Waveform Analysis in a Clinical Population

risk factors.To address this gap, we aimed to assess the relationship between pedometer-derived step counts and carotid-femoral pulse wave velocity (cfPWV), a summative measure of arterial health.Methods: 369 adults (46% men, 60% White, mean age 59.6AE11.2years, BMI 31.3AE4.5 kg/m 2 ) with hypertension and/or type 2 diabetes were recruited in Montreal, Canada (2011-2015).Step counts (Yamax SW-701 pedometer), moderate-to-vigorous physical activity (MVPA) (ActiGraph GT3x+), arterial stiffness (applanation tonometry; SphygmoCor), and cardiometabolic risk factors including blood pressure, haemoglobin AIc, and lipids were assessed.Results: Blood pressure was well-controlled (mean 125/77AE15/9 mmHg), low-density lipoprotein cholesterol (LDL-C) was close to target (mean 2.5AE1.0mmol/L), and A1c in diabetes was acceptable (mean 7.7AE1.3%).Participants averaged 5,125AE2,722 steps/day (low active) and mean cfPWV was 9.8AE2.2m/s.Step counts correlated with cfPWV, but not with any other cardiometabolic risk factors.A 1,000 step/day increment was associated with a 0.1m/s (95% CI -0.19, -0.02) decrement in cfPWV in a model adjusted for age, sex, BMI, ethnicity, immigration status, employment, education, diabetes, hypertension, medication classes, and MVPA. Conclusion:In patients with hypertension and/or diabetes who were wellcontrolled on cardioprotective medications, cfPWV is responsive to step counts and may emerge as a useful health indicator to track the arterial health impact of physical activity strategies in clinical practice.