Orthostatic hypotension can be a rare presenting symptom of left atrial myxoma due to mitral valve obstruction.
Clinicians may consider myxoma in unexplained orthostatic hypotension; single case extends spectrum but remains hypothesis-generating.
Cardiac tumors are divided into primary and secondary tumors. Primary cardiac tumors are very rare, with an autopsy incidence of 0.001% to 0.03%. Most (>80%) primary cardiac tumors are benign, and myxoma is by far the most common. Myxoma constitutes about 50% of all benign cardiac tumors in adults. Most myxomas (>80%) are found in the left atrium. We report a rare case of a massive left atrial myxoma causing mitral valve obstruction and presenting as positional dizziness. Though cardiac myxomas are known to present with various non-specific clinical symptoms, orthostatic hypotension is not listed as a presenting symptom of atrial tumors in most textbooks of internal medicine or cardiology. So this case is rare in this sense.
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Sandeep Kumar (2015) studied this question.
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