Why the study?
Does volume resuscitation affect heart rate variability in a pig model of hemorrhagic shock?
Does volume resuscitation affect heart rate variability in a pig model of hemorrhagic shock?
This preclinical study investigates the impact of volume resuscitation on heart rate variability as a measure of cardiac autonomic modulation during hemorrhagic shock.
Caution against applying pig-model HRV changes to patients; leaves open clinical relevance of volume resuscitation effects on autonomic modulation.
Hemorrhagic shock is responsible for high mortality rates in civilian injuries and combat casualties. The initial care of these patients comprehends an early assessment of hypovolemia, bleeding management and fluid resuscitation [ 1 ], while an adequate autonomic function is essential for maintaining the hemodynamic stability during haemorrhage. The analysis of heart rate variability (HRV) has been shown as a promising noninvasive technique for assessing the cardiac autonomic modulation in trauma, and several recent studies have demonstrated an association between HRV and clinical outcome [ 2 ].
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Salomão et al. (2014) studied this question.
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