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How do David and Yacoub valve-sparing procedures affect aortic root biomechanics compared to physiological and pathological states in a finite element model?
How do David and Yacoub valve-sparing procedures affect aortic root biomechanics compared to physiological and pathological states in a finite element model?
Finite element analysis suggests that while both David and Yacoub valve-sparing techniques restore coaptation and reduce stress, they alter leaflet kinematics, particularly the David repair.
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Altered leaflet kinematics after valve-sparing repairs merit clinical caution; leaves open durability effects and need for in vivo trials.
David and Yacoub sparing techniques are the most common procedures adopted for the surgical correction of aortic root aneurysms. These surgical procedures entail the replacement of the sinuses of Valsalva with a synthetic graft, inside which the cusps are re-suspended. Root replacement by a synthetic graft may result in altered valve behaviour both in terms of coaptation and stress distribution, thus leading to the failure of the correction. A finite element approach was used to investigate this phenomenon; four 3D models of the aortic root were developed to simulate the root in physiological, pathological and post-operative conditions after the two different surgical procedures. The physiological 3D geometrical model was developed on the basis of anatomical data obtained from echocardiographic images; it was then modified to obtain the pathological and post-operative models. The effectiveness of both techniques was assessed by comparison with the first two simulated conditions, in terms of stresses acting on the root, leaflet coaptation and interaction between leaflets and the graft during valve opening. Results show that both sparing techniques are able to restore aortic valve coaptation and to reduce stresses induced by the initial root dilation. Nonetheless, both techniques lead to altered leaflet kinematics, with more evident alterations after David repair.
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Soncini et al. (2008) studied this question.
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