Chondrosarcoma of the mobile spine: impact of tumor status at referral and surgical strategy on oncological outcome

Isabella Giannini; Loredana Mavilla; Shi Benchao; Riccardo Ghermandi; Stefano Boriani; Alessandro Gasbarrini

doi:10.1007/s00586-026-10165-2

August 3, 2026European Spine JournalOpen Access

Chondrosarcoma of the mobile spine: impact of tumor status at referral and surgical strategy on oncological outcome

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Key Points

This study aims to evaluate the prognostic role of tumor status at referral and compare local recurrence-free survival after different surgical strategies for low-grade chondrosarcoma.
Retrospective observational study of 91 treatments in 67 patients over 40 years at a tertiary center.
Comparison of local recurrence rates after en bloc resection and intralesional surgery with/without particle therapy or conventional radiotherapy.
Analysis of tumor status defined as 'intact' (treatment-naive) and 'not-intact' (previously treated).
Overall local recurrence rate was 40.6%, with 21.7% for 'intact' tumors and 60.0% for 'not-intact' tumors (p < 0.001).
En bloc resection resulted in a 13.1% local recurrence rate versus 60.4% for intralesional procedures (p < 0.001).
Combination of particle therapy with intralesional surgery had a 55.6% recurrence rate, significantly higher than the 13.9% for en bloc resection alone (p = 0.0028).

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Implication

Retrospective study evaluates the impact of tumor status and surgical strategy on local recurrence in low-grade chondrosarcoma of the spine, suggesting en bloc resection offers better outcomes.

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Giannini et al. (2026) studied this question.

synapsesocial.com/papers/6a72e7d2226790f3706570fb https://doi.org/10.1007/s00586-026-10165-2

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Chondrosarcoma of the mobile spine: impact of tumor status at referral and surgical strategy on oncological outcome

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Chondrosarcoma of the mobile spine: impact of tumor status at referral and surgical strategy on oncological outcome

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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