Theoretical model demonstrates increased energy demands for membrane homeostasis under nanoparticle stress, suggesting implications for cellular integrity.
Living cells continuously maintain the structural and functional integrity of their plasma membrane despite persistent exposure to mechanical, chemical, and environmental stress. Among emerging environmental factors, engineered and environmental nanoparticles represent a growing source of mechanical perturbation. This paper proposes a theoretical biophysical model describing how repeated nanoparticle-induced mechanical stress may increase the energetic demands required to preserve membrane homeostasis.
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Peter Mikuláš (2026) studied this question.
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