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August 5, 2026Chemistry - A European Journal

Novel Multi‐Doped Apatite‐Related Calcium Phosphates and Composites With SiO 2 for Medical Application

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Authors

NSNataliia StrutynskaTaras Shevchenko National University of KyivYKYeva KomashchenkoTaras Shevchenko National University of KyivІGІ. І. GrynyukNational Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”

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Implication

Randomized trial shows enhanced antimicrobial and mechanical properties in calcium phosphate composites, suggesting new bioactive materials for medical use.

Key Points

  • This study aims to synthesize and characterize multi-doped hydroxyapatites and their composites for medical applications.
  • Synthesis of multi-doped hydroxyapatites with Na+, Mg2+, Zn2+ and various anions including SiO4^4-, CO3^2-, BO3^3-, and BO2-
  • Characterization using XRD and FTIR to analyze structural and mechanical properties
  • Assessment of biological properties including antimicrobial activity against bacteria like Staphylococcus aureus and Pseudomonas aeruginosa.
  • Composite of (Na+, Mg2+, Zn2+, CO3^2−)-doped HAP with 25 wt% SiO2 showed the highest antimicrobial activity, outperforming borate analogues by 1.36–1.89 times
  • Material demonstrated excellent mechanical performance with microhardness ∼0.32–0.33 GPa
  • Successful tailoring of surface reactivity indicated by pH elevation to 8.2–9.4 without significant degradation.

Cite This Study

Strutynska et al. (2026) studied this question.

synapsesocial.com/papers/6a72e84e226790f370658086https://doi.org/10.1002/chem.71505
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