What question did this study set out to answer?

To determine whether serum uric acid levels correlate with blood pressure in children and adolescents presenting with new-onset, untreated primary hypertension.

August 5, 2003HypertensionOpen Access

Hyperuricemia in Childhood Primary Hypertension

View Full Paper

Ask AI

Bookmark

To determine whether serum uric acid levels correlate with blood pressure in children and adolescents presenting with new-onset, untreated primary hypertension.
Evaluated 125 consecutive untreated patients aged 6 to 18 years (mean 13.4±3.3) with normal renal function (creatinine clearance >80 mL/min/1.73 m²), categorized into primary hypertension (n=63), secondary hypertension (n=40), or white-coat hypertension (n=22).
Recruited 40 normotensive controls from a pediatric renal clinic to assess blood pressure correlations against serum uric acid concentrations.
Serum uric acid directly correlated with systolic (r=0.80, P=0.0002) and diastolic (r=0.66, P=0.0006) blood pressure across controls and subjects with primary hypertension, independent of renal function.
Serum uric acid concentrations exceeding 5.5 mg/dL occurred in 89% of children with primary hypertension, 30% with secondary hypertension, 0% with white-coat hypertension, and 0% of normotensive controls.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Observational study reveals serum uric acid strongly correlates with blood pressure in pediatric primary hypertension, suggesting a role in early pathogenesis.

Cite This Study

Feig et al. (2003) studied this question.

synapsesocial.com/papers/6a72eaa5e04c15aa3360d7ad https://doi.org/10.1161/01.hyp.0000085858.66548.59

View Full Paper

Ask AI

Bookmark

Implication

Observational study reveals serum uric acid strongly correlates with blood pressure in pediatric primary hypertension, suggesting a role in early pathogenesis.

Hyperuricemia in Childhood Primary Hypertension

Key Points

Discussion

Implication

Cite This Study

Hyperuricemia in Childhood Primary Hypertension

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider