Answers are grounded in this paper and cite their sources.
Lymphocytes transferred from 6-day-old human mixed lymphocyte cultures (MLC) inhibited the response to allogeneic cells of freshly taken lymphocytes autologous to the transferred MLC-responding cells. No specificity for this cell-dependent suppression could be determined. The inhibitory effects of the suppressing cells could be abrogated by moderate X-ray irradiation and significantly reduced by pretreating them with an anti-Ia-like antiserum and complement. The human suppressor cell responsible for the observed effects therefore appears to carry determinants equivalent to the murine Ia alloantigens.
No takes yet. Share an insight, caveat, or question.
Hirschberg et al. (1977) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: