Assembly of type I collagen fibrils de novo. Between 37 and 41 degrees C the process is limited by micro-unfolding of monomers.

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Assembly of collagen fibrils de novo by cleavage of the type I pC-collagen with procollagen C-proteinase. Assay of critical concentration demonstrates that collagen self-assembly is a classical example of an entropy-driven process.1987 · 332 citations
2. 2Thermal stability of the triple helix of type I procollagen and collagen. Precautions for minimizing ultraviolet damage to proteins during circular dichroism studies1979 · 99 citations
3. 3The formation of fibrils from collagen solutions. 2. A mechanism for collagen-fibril formation1960 · 189 citations
4. 4The role of hydrophobic bonding in collagen fibril formation: A quantitative model1985 · 22 citations
5. 5Collagen self-assembly in vitro. Differentiating specific telopeptide-dependent interactions using selective enzyme modification and the addition of free amino telopeptide.1981 · 213 citations