Why the study?
Does veno-arterial extracorporeal membrane oxygenation (VA ECMO) improve left ventricular function in neonates with myocardial infarction?
Does veno-arterial extracorporeal membrane oxygenation (VA ECMO) improve left ventricular function in neonates with myocardial infarction?
Early referral for VA ECMO can provide crucial cardiorespiratory support allowing for the recovery of left ventricular function in neonates with acute myocardial infarction.
Cautions against routine adoption from single case; leaves open whether prolonged VA ECMO improves outcomes in neonatal MI.
Acute myocardial infarction is a cause of neonatal collapse. The diagnosis is suggested by ischaemic electrocardiography, raised cardiac enzymes and deteriorating cardiac function and should be considered in severe neonatal cardiac dysfunction without other identifiable causes. This paper presents four cases of neonatal myocardial infarction treated with veno-arterial extracorporeal membrane oxygenation (VA ECMO) for cardiorespiratory support. The paper illustrates that left ventricular function may recover after neonatal myocardial infarction if it can be supported for long enough, and that early ECMO referral may be of benefit.
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Ferns et al. (2007) studied this question.
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