Why the study?
Hypertension is a major risk factor for coronary artery disease, and evaluating cardiac changes using echocardiography helps assess its impact on left ventricular function.
Does chronic hypertension affect echocardiographic parameters of left ventricular function in patients over 60 years of age?
Does chronic hypertension affect echocardiographic parameters of left ventricular function in patients over 60 years of age?
Chronic hypertension for over 5 years in patients older than 60 is associated with significant structural echocardiographic changes compared to healthy controls, despite systolic function remaining within normal limits.
Stress echocardiography offers satisfactory CAD diagnostic accuracy in hypertension; leaves open need for prospective outcome trials before practice change.
Introduction: Hypertension is a major risk factor for the development of coronary artery disease (CAD), the reliability of stress testing for the evaluation of chest pain in patients with abnormal blood pressure elevation is an important clinical problem. When compared to exercise electrocardiography, stress echocardiography (SE) provides similar sensitivity but superior diagnostic specificity. Materials and Methods: A cross-sectional study was conducted in the Department of Physiology in collaboration with echocardiography lab of Santosh Medical hospital Ghaziabad, on a population of 200 cases more than 60 years of age. Amongst these patients, 100 patients with hypertension for more than 5 years were included in Group 1 and 100 healthy age matched control were included in Group 2. Physical parameters were recorded and all subjects underwent comprehensive echocardiographic examination. Data was analysed using SPSS 20 software. All parameters were presented as mean and standard deviation. A p-value Results: Gender distribution was 86% Male and 14% female in case group and 91% Male and 9% female subjects in control group. In echocardiographic parameters, the difference in values of L.A. Diameter in Group 1(2.94+0.27) vs Group 2 (3.43+0.32) was significant. Similarly, difference in value of Aortic Root in Group 1(2.94+0.27) vs Group 2 (3.02+0.32) was significant. The difference in value of IVSD in Group 1 (2.94+0.27) vs Group 2 (3.02+0.32) was also significant. However, difference in values of LVID in Group 1 (4.97+4.25) vs Group 2 (5.24+5.) was not statistically significant. Conclusion: In current study, Left ventricular systolic function was within normal physiological limits in all hypertensive patients. However, when compared to healthy control group it was lower suggesting that chronic hypertension does affect left ventricular function gradually.
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Garg et al. (2020) studied this question.
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