Why the study?
Neonates with congenital heart disease are at high risk of vascular thrombosis due to vascular injury, increased blood viscosity, or low cardiac output stasis.
A novel approach for recanalization and limb saving was utilized in two neonates with acute upper limb arterial thrombosis following congenital heart surgery.
Hypothesis-generating in high-risk neonates; leaves open whether targeted prophylaxis trials are warranted.
Neonates with congenital heart disease are at a high risk of vascular thrombosis. Thrombosis may occur due to vascular injury, increased blood viscosity secondary to polycythemia associated with congenital cyanotic heart diseases, or stasis of blood flow associated with low cardiac output (Schmidt B & Andrew M., Pediatrics 1995; 96: 939-943. Veldman A et al.,Vasc Health Risk Manag 2008; 4: 1337-1348).
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Ata et al. (2020) studied this question.
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