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May 1, 2022International Journal of General MedicineOpen Access

The nomogram achieved a Harrell's C-index of 0.773 (95% CI: 0.726-0.821) in the training set and 0.758 (95% CI: 0.679-0.837) in the validation set.

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Why the study?

The study was conducted to develop a nomogram model that predicts the risk of diabetic nephropathy incidence in type 2 diabetes mellitus patients.

Can a 7-factor nomogram model accurately predict the risk of diabetic nephropathy incidence in patients with type 2 diabetes mellitus?

Population

T2DM patients split into a training set (n=521) and validation set (n=185)

Design

Cross-sectional study

Authors

JYJing YangSJSheng Jiang

Discussion

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Member takes

Overview

May aid DN risk stratification in T2DM; leaves open need for prospective validation before clinical adoption.

Structured PICO

Can a 7-factor nomogram model accurately predict the risk of diabetic nephropathy incidence in patients with type 2 diabetes mellitus?

P
Population
706 patients with Type 2 Diabetes Mellitus (T2DM), split into a training set (n=521) and a validation set (n=185).
I
Intervention
A 7-factor nomogram predictive model incorporating serum creatinine (Scr), hypertension, glycosylated hemoglobin A1c (HbA1c), blood urea nitrogen (BUN), body mass index (BMI), triglycerides (TG), and diabetic peripheral neuropathy (DPN).
O
Outcome
Incidence of diabetic nephropathy (DN) and model predictive accuracy (measured by Harrell's C-index).

A novel 7-factor nomogram demonstrates good discriminative ability and clinical value for predicting the risk of diabetic nephropathy in patients with type 2 diabetes mellitus.

Cite This Study

Yang et al. (2022) studied this question.

synapsesocial.com/papers/6a72f12a64f3cafe06cf2aa0https://doi.org/10.2147/ijgm.s363474
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Construction of a Nomogram Prediction Model for the Risk of Type 2 Diabetic Peripheral Neuropathy2024
  2. 2Development and validation of a risk nomogram model for predicting peripheral neuropathy in patients with type 2 diabetes mellitus2024 · 3 citations
  3. 3Development of a Predictive Model and Nomogram for Neuropathy Risk in T2DM Patients2025
  4. 4Development and validation of a nomogram model for predicting diabetic foot in type 2 diabetes2026
  5. 5Development and validation of a nomogram model for individualized prediction of hypertension risk in patients with type 2 diabetes mellitus2023 · 18 citations