May 1, 2011Memórias do Instituto Oswaldo CruzOpen Access

Human rhinovirus in the lower respiratory tract infections of young children and the possible involvement of a secondary respiratory viral agent

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Why the study?

Does co-infection with a second respiratory virus increase the frequency of severe disease in children with HRV-associated lower respiratory tract illness?

Population

83 children diagnosed with lower respiratory tract illness who were positive for human rhinovirus RNA…

Comparison

Co-infection with a second respiratory virus vs Infection with HRV alone

Design

Cohort

Authors

NPNayhanne Tizzo de PaulaFundação Oswaldo Cruz BCBruno Moreira CarneiroUniversidade Federal de Rondônia JYJonny YokosawaUniversidade Federal de Uberlândia

Discussion

Member takes

Implication

Co-infection was not associated with increased severity in pediatric HRV LRTI; leaves open whether specific viral pairs affect outcomes in larger cohorts.

Structured PICO

Does co-infection with a second respiratory virus increase the frequency of severe disease in children with HRV-associated lower respiratory tract illness?

Population

83 children diagnosed with lower respiratory tract illness (LRTI) who were positive for human rhinovirus (HRV) RNA, selected from 532 nasopharyngeal aspirates collected over a nine-year period at the Clinics Hospital of Uberlândia.

Intervention

Co-infection with a second respiratory virus

Comparator

Infection with HRV alone

Outcome

Frequency of severe diseasehard clinical

Co-infection with a second respiratory virus does not appear to increase the severity of lower respiratory tract illness in children infected with human rhinovirus.

Cite This Study

Paula et al. (2011) studied this question.

synapsesocial.com/papers/6a72f1d930ce5f18cc1cf587 https://doi.org/10.1590/s0074-02762011000300010

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Implication

Co-infection was not associated with increased severity in pediatric HRV LRTI; leaves open whether specific viral pairs affect outcomes in larger cohorts.

Human rhinovirus in the lower respiratory tract infections of young children and the possible involvement of a secondary respiratory viral agent

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Human rhinovirus in the lower respiratory tract infections of young children and the possible involvement of a secondary respiratory viral agent

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider