Some transformations involving AuCl(PPh3) in CH3CN/H2O solution are considered and a comparison is made with known data for auranofin. Interaction with GSH leads to the formation of a binuclear (GSH)[Au(PPh3)]2 (at CGSH/CAu 0.5) or mononuclear Au(GSH)(PPh3) (CGSH/CAu 0.5) complex; PPh3 substitution is not observed. Interaction with BSA leads to Cl– substitution. A cyclic voltammetry study showed the presence of several peaks of irreversible oxidation of AuCl(PPh3) and complexes with GSH.
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Миронов et al. (2024) studied this question.
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