Key result
Patients with ≥3 acute risk factors were more likely to receive aspirin at presentation than those with zero (85.7% vs 81.1%, P<0.001), while those with ≥4 chronic risk factors were less likely.
Observational (n=2,599)
Yes
Absolute Event Rate: 85.7% vs 81.1%
p-value: p=<0.001
In patients with acute coronary syndromes, the presence of multiple chronic comorbidities paradoxically reduces the likelihood of receiving evidence-based treatments, highlighting a critical gap in quality of care.
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May signal undertreatment in ACS patients with high chronic comorbidity burden; leaves open whether targeted interventions improve guideline adherence.
Joynt et al. (2009) conducted an observational in Acute coronary syndromes (n=2,599). Acute and chronic risk factors vs. Zero acute or chronic risk factors was evaluated on Use of evidence-based treatments (e.g., aspirin at presentation) (p=<0.001). Patients with ≥3 acute risk factors were more likely to receive aspirin at presentation than those with zero (85.7% vs 81.1%, P<0.001), while those with ≥4 chronic risk factors were less likely.
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