Key result
Steroids and aspirin initially reversed complete atrioventricular block after transcatheter VSD closure, but the block reappeared and required definitive pacemaker implantation.
Why the study?
Is steroid and aspirin therapy sufficient to permanently reverse complete atrioventricular block after percutaneous perimembranous ventricular septal defect closure?
Case Report (n=1)
Is steroid and aspirin therapy sufficient to permanently reverse complete atrioventricular block after percutaneous perimembranous ventricular septal defect closure?
Steroid and aspirin therapy may not be sufficient to permanently reverse complete atrioventricular block following transcatheter closure of perimembranous ventricular septal defects, and patients may still require pacemaker implantation.
Answers are grounded in this paper and cite their sources.
May not durably reverse post-closure AV block; leaves open whether adjunctive strategies can avert pacemaker implantation.
Due to the close proximity of the perimembranous ventricular septal defect to the conduction system, complete atrioventricular block may occur after transcatheter closure in around 1-5% of cases. Some authors reported on successful use of steroids and aspirin in reversing complete atrioventricular heart block early after transcatheter closure of perimembranous ventricular septal defect using the Amplatzer membranous ventricular septal defect occluder. In this paper, we report a case of reappearance of complete atrioventricular block requiring a definitive pacemaker implantation after an initial successful reversal using both steroids and aspirin.
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Butera et al. (2009) conducted a case report in Complete atrioventricular block after transcatheter closure of perimembranous ventricular septal defect (n=1). Steroids and aspirin was evaluated on Reversal of complete atrioventricular block. Steroids and aspirin initially reversed complete atrioventricular block after transcatheter VSD closure, but the block reappeared and required definitive pacemaker implantation.
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