Key result
Pre-operative aerobic exercise combined with standard medical care significantly reduced the length of hospital stay (41.32 vs 56.7 hours) compared to standard care alone in patients undergoing bariatric surgery.
Why the study?
To examine the effect of pre-operative aerobic exercise combined with standard medical care compared to standard care alone on cardiometabolic health, quality of life, and surgical outcomes in patients undergoing bariatric surgery.
Does pre-operative aerobic exercise combined with standard medical care improve cardiometabolic health, quality of life, and surgical outcomes in patients undergoing bariatric surgery?
Does pre-operative aerobic exercise combined with standard medical care improve cardiometabolic health, quality of life, and surgical outcomes in patients undergoing bariatric surgery?
Standardized Mean Difference: 1.38
Absolute Event Rate: 41.32% vs 56.7%
p-value: p=0.05
Adding 30 days of aerobic exercise to standard medical care prior to bariatric surgery may reduce hospital length of stay and improve quality of life and cardiometabolic markers.
May shorten bariatric hospital stay; leaves open confirmation in randomized trials.
Objective. Examine the effect of aerobic exercise (EX) combined with standard medical care (SC) (EX+SC) compared to SC alone on cardiometabolic health and quality of life in relation to surgical outcomes. Methods. Patients receiving bariatric surgery were match-paired to 30 d of pre-operative SC (n=7, 1 male, 39.05.3 y, body mass index 46.4±3.0 kg/m2; low calorie diet) or EX+SC (n = 7, 0 males, 45.64.8 y, body mass index 43.9±4.2 kg/m2; walking 30min/d, 5d/wk, 65-85% HRpeak). Body mass, waist circumference, cardiorespiratory fitness (VO2peak), high sensitivity C-reactive protein (hs-CRP), cytokeratin 18 (CK18), weight related quality of life (QoL), and a 120 min mixed meal tolerance test (MMTT) was performed to assess arterial stiffness via augmentation index normalized to a heart rate of 75 beats per minute (AIx@75), whole-body insulin sensitivity, and glucose total area under the curve (tAUC) pre- and post-intervention (~2 d prior to surgery). Length of hospital stay (admission to discharge) was recorded. Results. EX+SC had a greater effect for decreased intake of total calories (P=0.14; ES=0.86) compared to SC, but no change in body weight or waist circumference was observed in either group. EX+SC had a greater effect for increased VO2peak (P=0.24; ES=0.91) and decreased hs-CRP (P=0.31; ES=0.69) compared to SC. EX+SC reduced circulating CK18 (P=0.05; ES=3.05) and improved QoL (P=0.02) compared to SC. Although EX+SC had no statistical effect on arterial stiffness compared to SC, we observed a modest effect size for AIx@75 tAUC (P=0.36; ES=0.52). EX+SC had a significantly shorter length of hospital stay (P=0.05; ES=1.38) than SC, and a shorter length of hospital stay was associated with decreased sugar intake (r=0.55, P=0.04). Decreased AIx@75 tAUC significantly correlated with improved whole-body insulin sensitivity (r=-0.59, P=0.03) and glucose tAUC (r=0.57, P=0.04). Conclusion. EX with SC for 30 days prior to bariatric surgery may be important for cardiometabolic health, quality of life, and surgical outcomes in the bariatric patient.
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Gilbertson et al. (2020) studied Morbid obesity (n=14). Aerobic exercise combined with standard medical care (EX + SC) vs. Standard medical care (SC) alone (low calorie diet) was evaluated on Length of hospital stay (ES 1.38, p=0.05). Pre-operative aerobic exercise combined with standard medical care significantly reduced the length of hospital stay (41.32 vs 56.7 hours) compared to standard care alone in patients undergoing bariatric surgery.
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