What question did this study set out to answer?

Determine the therapeutic role and survival impact of surgical resection in patients diagnosed with malignant abdominal mesothelioma.

October 21, 2008Journal of Surgical Oncology

Malignant abdominal mesothelioma: Defining the role of surgery

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Determine the therapeutic role and survival impact of surgical resection in patients diagnosed with malignant abdominal mesothelioma.
Queried the Surveillance, Epidemiology, and End Results (SEER) database for cases diagnosed between 1973 and 2005.
Identified 10,589 total malignant mesothelioma cases, categorized into thoracic (N=9,211) and abdominal (N=1,112) presentations.
Malignant abdominal mesothelioma accounted for 10.5% of cases, occurring at a younger median age (63 vs. 71 years, P < 0.001) and with less localized disease than thoracic presentations (P < 0.001).
Surgical resection resulted in significantly longer median survival (20 months vs. 4 months, P < 0.001) and higher 5-year survival rates (28% vs. 12%, P < 0.001).
Multivariate analysis showed that omitting surgical resection, poorly differentiated tumor grade, advanced age, and male sex were independent predictors of poorer survival.

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Implication

Retrospective registry study reveals improved survival after surgical resection in malignant abdominal mesothelioma, indicating all patients should be evaluated for surgery.

Cite This Study

Rodríguez et al. (2008) studied this question.

synapsesocial.com/papers/6a730ba7ffe2eab417a8f660 https://doi.org/10.1002/jso.21167

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Implication

Retrospective registry study reveals improved survival after surgical resection in malignant abdominal mesothelioma, indicating all patients should be evaluated for surgery.

Malignant abdominal mesothelioma: Defining the role of surgery

Key Points

Discussion

Implication

Cite This Study

Malignant abdominal mesothelioma: Defining the role of surgery

Key Points

Discussion

Implication

Cite This Study

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