Key result
An 88-year-old male with an asymptomatic SARS-CoV-2 infection developed a high-degree atrioventricular block requiring permanent pacemaker implantation.
Why the study?
Reports of cardiac conduction system disturbances from COVID-19 infection are rare, particularly in patients lacking other signs of cardiac involvement or respiratory symptoms.
Case Report (n=1)
No
Asymptomatic COVID-19 infection can rarely present with isolated cardiac conduction system involvement, such as high-degree AV block requiring permanent pacing.
May link asymptomatic SARS-CoV-2 to high-degree AV block in elderly; hypothesis-generating and should not change practice.
The first cases of COVID-19 infection were reported as pneumonia of unknown cause in China in December 2019. While respiratory complications remain the hallmark of the disease, multisystem involvement has been well documented. Cardiovascular involvement with potentially lethal myocarditis has been extensively reported in the literature. Reports of conduction system disturbances are much rarer, especially in patients without other signs of cardiac involvement. We present a case of an 88-year-old male with no prior cardiac history who presented to the hospital with obstipation. He was diagnosed with a small bowel obstruction and underwent a lysis of adhesions. During the hospitalization, he developed intermittent bradycardia with a high-degree atrioventricular (AV) block. A decision was made to implant a permanent pacemaker. During a pre-procedure COVID-19 screen, he was found to be positive for the presence of SARS-CoV-2 RNA. He had no signs of myocardial injury, a transthoracic echocardiogram showed no abnormalities, and he remained free of any respiratory symptoms. While the involvement of the cardiac conduction system has been documented in patients with symptomatic COVID-19 infection, our patient only exhibited conduction abnormalities and remained free of other COVID-19 symptoms. The sole involvement of the conduction system by COVID-19 is rare, especially in patients with otherwise asymptomatic infections. There is no long-term data to suggest whether such conduction abnormalities are temporary or permanent. As such, patients might benefit from the implantation of a permanent pacemaker.
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Maisuradze et al. (2022) conducted a case report in Asymptomatic COVID-19 infection (n=1). Asymptomatic SARS-CoV-2 infection was evaluated on High-degree atrioventricular block. An 88-year-old male with an asymptomatic SARS-CoV-2 infection developed a high-degree atrioventricular block requiring permanent pacemaker implantation.
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