Key result
Cardiac surgery in octogenarians resulted in an 8% operative mortality and a mean survival of 8.8 years (95% CI 7.6-10.1), with complex procedures predicting death (p<0.05).
Why the study?
What are the long-term survival and functional outcomes following cardiac surgery in octogenarians?
Cohort (n=66)
What are the long-term survival and functional outcomes following cardiac surgery in octogenarians?
Effect estimate: Mean survival 8.8 years (95% CI 7.6-10.1)
Cardiac surgery in octogenarians yields good long-term survival and functional outcomes, though complex or emergency procedures significantly increase mortality risk.
May inform shared decisions for selected octogenarians; leaves open prospective validation of functional outcomes and selection criteria.
OBJECTIVE: Cardiac surgery for patients >80 years has seen a dramatic increase in the last decade. The aim was to assess the long term survival and quality of life in this patient population. METHOD: Patients who underwent cardiac surgery between 1995 and 2007 were identified and case notes reviewed. Follow-up was undertaken by personal interview with the patient or the nearest kin to complete a pre-planned questionnaire. RESULTS: Sixty six (M:F; 45:21) octogenarians had Coronary artery bypass grafting (CABG) only (55%), Aortic valve replacement (AVR) only (12%), Mitral valve replacement (MVR) only (3%), Valve and CABG (25%) and complex procedures (5%). Fifty-eight percent were elective procedures. Operative mortality was 8% (n = 5). Multivariate analysis identified complex procedures, prolonged bypass time and re-do/emergency surgery as predictors of death (p < 0.05). Median Intensive care unit (ICU) stay was 206 h (range 43-1176 h), with >70% leaving ICU in 72 h. Late mortality involved five patients (8%) who died at 10 yr; 7 yr; 3 yr; 1 yr; and 8 months; and 2 yr and 7 months, respectively. Survival by Kaplan-Meir was 8.8 yr (Standard Error (SE) = 0.66, Confidence interval (CI) 7.6-10.1), median survival was 10 yr and mean Barthel's index 17.7 (min 0, max 20). CONCLUSIONS: Cardiac surgery can be accomplished in octogenarians with good long-term survival and quality of life. However, complex procedures, prolonged bypass and re-do/emergency surgery contribute significantly to mortality.
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Nwaejike et al. (2009) conducted a cohort in Cardiac surgery in octogenarians (n=66). Cardiac surgery was evaluated on Long term survival (Mean survival 8.8 years, 95% CI 7.6-10.1). Cardiac surgery in octogenarians resulted in an 8% operative mortality and a mean survival of 8.8 years (95% CI 7.6-10.1), with complex procedures predicting death (p<0.05).
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