March 1, 2000Journal of neurosurgery
Neurosurgical implications of Carney complex
Key result
Among 14 pituitary adenomas associated with Carney complex, 12 developed growth hormone hypersecretion, producing gigantism in two patients and acromegaly in 10.
Population
14 patients with Carney complex (9 from authors' experience, 5 from literature)
Design
Case_series
Authors
Discussion
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Implication
Recognition of Carney complex in GH-secreting adenomas warrants cardiac evaluation and family screening; case-level data leave open broader recommendations.
Study Design
Type
Case Report (n=14)
Structured PICO
P
Population
14 cases of Carney complex (9 from authors' experience, 5 from literature) evaluated for neurosurgical implications including pituitary adenomas and nerve sheath tumors.
Recognition of Carney complex is important for neurosurgeons due to the surgical comorbidity associated with cardiac myxomas and Cushing's syndrome, and the need for family screening.
Cite This Study
Watson et al. (2000) conducted a case report in Carney complex (n=14). Carney complex was evaluated on Growth hormone hypersecretion in pituitary adenomas. Among 14 pituitary adenomas associated with Carney complex, 12 developed growth hormone hypersecretion, producing gigantism in two patients and acromegaly in 10.