Case report demonstrates reduced fluid accumulation and increased albumin from ascites reinfusion therapy and chemotherapy in lung adenocarcinoma, highlighting a viable management strategy.
We report the case of a 65-year-old woman with stage IVB lung adenocarcinoma who developed malignant ascites during treatment. Despite multiple ascitic fluid drainages and second-line chemotherapy, the ascites progressively worsened. The initiation of cell-free and concentrated ascites reinfusion therapy (CART) led to improved abdominal distention, increased blood albumin levels, and slower ascites accumulation. To our knowledge, this is the first report of CART combined with chemotherapy for the management of malignant ascites associated with lung cancer.
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Jingo et al. (2025) studied this question.
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