Is Mediation of Sweating Cholinergic, Adrenergic, or Both? A Comment on the Literature

Research on SNS mediation of human eccrine and apocrine sweating was examined. Both types of sweat glands in humans are innervated primarily by cholinergic fibers and, at least sparsely, by adrenergic fibers. Both types of sweat glands are also stimulated by circulating catecholamines, but the mechanism for this action has not been unequivocally established. Recent research developments in the physiology of the sweat glands are discussed as they bear on persistent problems in psycho physiological research.