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June 25, 2018Journal of Pharmaceutical Health Services Research

Investigation of variables associated with medication nonadherence in patients with hypertension

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Key result

Poor health-related quality of life (OR 0.127; 95% CI 0.04-0.87) and concerns about side effects (OR 0.165; 95% CI 0.09-0.95) were strongly associated with medication nonadherence in hypertension.

Why the study?

What are the predictors of medication nonadherence in patients with hypertension?

Population

300 patients with hypertension attending three major hospitals in Jordan

Design

Cross-sectional

Authors

AJAnan S. JarabEAEman AlefishatRNRasha Bani Nasur

Discussion

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Member takes

Overview

May inform adherence counseling in hypertension; leaves open whether targeting these factors improves outcomes.

Study Design

Type

Cross-Sectional (n=300)

Multicenter

Yes

Structured PICO

What are the predictors of medication nonadherence in patients with hypertension?

P
Population
300 patients with hypertension attending three major hospitals in Jordan assessed for medication adherence and health-related quality of life.
O
Outcome
Medication nonadherencepatient reported

Main Result

Odds Ratio: 0.127 (95% CI 0.04–0.87)

Polypharmacy, comorbidities, side effect concerns, and poor quality of life are major predictors of medication nonadherence in hypertensive patients.

Cite This Study

Jarab et al. (2018) conducted a cross-sectional in hypertension (n=300). Poor health-related quality of life vs. Better health-related quality of life was evaluated on Medication nonadherence (OR 0.127, 95% CI 0.04-0.87). Poor health-related quality of life (OR 0.127; 95% CI 0.04-0.87) and concerns about side effects (OR 0.165; 95% CI 0.09-0.95) were strongly associated with medication nonadherence in hypertension.

synapsesocial.com/papers/6a731ce5ca0cfc242ec23156https://doi.org/10.1111/jphs.12236
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Medication adherence in patients with hypertension: Does satisfaction with doctor-patient relationship work?2017 · 57 citations
  2. 2Predictors of non-adherence to antihypertensive medication in Kinshasa, Democratic Republic of Congo: a cross-sectional study2015 · 73 citations
  3. 3Predictors of adherence to medication in older Korean patients with hypertension2011 · 52 citations
  4. 4Determinants of Adherence to Treatment in Hypertensive Patients of African Descent and the Role of Culturally Appropriate Education2015 · 43 citations
  5. 5Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence1986 · 5,381 citations