Key result
Musculoskeletal ultrasound detecting sub-clinical synovitis or bone erosions greatly increases the predicted risk of developing inflammatory arthritis in individuals at-risk for rheumatoid arthritis.
Why the study?
Identifying biomarkers that detect individuals at imminent risk of progression to rheumatoid arthritis is crucial for disease prevention.
Does musculoskeletal ultrasound predict progression to inflammatory arthritis in individuals at-risk of rheumatoid arthritis without clinical synovitis?
Population
Individuals at-risk of RA with musculoskeletal symptoms but no clinical evidence of IA
Design
Review
Authors
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May enhance risk stratification in at-risk RA; leaves open prospective validation before practice change.
Does musculoskeletal ultrasound predict progression to inflammatory arthritis in individuals at-risk of rheumatoid arthritis without clinical synovitis?
Musculoskeletal ultrasound can detect sub-clinical synovitis and bone erosions, aiding in the early identification of at-risk individuals who will progress to inflammatory arthritis.
Matteo et al. (2021) conducted a review in Individuals 'at-risk' of rheumatoid arthritis. Musculoskeletal ultrasound was evaluated on Progression to inflammatory arthritis. Musculoskeletal ultrasound detecting sub-clinical synovitis or bone erosions greatly increases the predicted risk of developing inflammatory arthritis in individuals at-risk for rheumatoid arthritis.
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