Key result
A 46-year-old man with acute pericarditis mimicking unstable angina pectoris experienced complete resolution of symptoms and pericardial effusion after 3 weeks of colchicine and ibuprofen therapy.
Why the study?
Pericarditis clinical features may not always match written theory, which can lead to misdiagnosis in settings such as the emergency department.
Case Report (n=1)
Acute pericarditis can present atypically and mimic acute coronary syndrome, highlighting the importance of considering differential diagnoses and utilizing echocardiography to avoid misdiagnosis.
May support colchicine-ibuprofen for pericarditis mimicking ACS; hypothesis-generating single case leaves generalizability open.
Pericarditis is a common disorder that might present in various settings, including primary-care and emergency department. However, the clinical features in some cases did not match with the written theory, which could lead to a misdiagnosis. A 46-year-old man presented to the emergency room with progressive tightness chest pain, epigastric pain, nausea, and vomiting in the past 2 days. Based on the clinical, electrocardiograph (ECG), and laboratory evaluation, the patient was diagnosed with unstable angina pectoris and treated accordingly but did not showed an improvement. Clinical re-examination and echocardiography evaluation showed a pathognomonic finding of pericarditis feature. Combination therapy of colchicine and ibuprofen was given for 3 weeks. One-month follow-up evaluation showed normal ECG and echocardiography result without any remaining symptoms. Acute pericarditis does not always show typical finding. Therefore, clinician must always aware with other differential diagnosis of chest pain and ECG variation of acute pericarditis.
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Intan et al. (2019) conducted a case report in Acute Pericarditis (n=1). Colchicine and ibuprofen was evaluated on Resolution of symptoms, ECG abnormalities, and pericardial effusion. A 46-year-old man with acute pericarditis mimicking unstable angina pectoris experienced complete resolution of symptoms and pericardial effusion after 3 weeks of colchicine and ibuprofen therapy.
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