Why the study?
Does serum SGO-T activity correlate with the extent of myocardial infarction in dogs?
Population
Dogs with experimentally induced graded myocardial infarcts
Comparison
Graded myocardial infarction vs Normal muscle / pre-infarction baseline
Design
Preclinical
Authors
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Supports SGO-T as necrosis marker in canine models; leaves open human translation for infarct sizing.
Does serum SGO-T activity correlate with the extent of myocardial infarction in dogs?
Serum SGO-T activity is a sensitive biomarker that rises proportionally to the extent of myocardial necrosis in a canine model of myocardial infarction.
Nydick et al. (1955) studied this question.
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