Key result
High fall risk is linked to ~30% higher odds of therapeutic inertia in uncontrolled BP.
Why the study?
Therapeutic inertia in BP management increases with age and may in part be driven by perceived fall risk.
Is questionnaire-assessed fall risk severity associated with uncontrolled blood pressure and therapeutic inertia during primary care visits among older adults with hypertension?
Cohort (n=13,893)
Yes
Is questionnaire-assessed fall risk severity associated with uncontrolled blood pressure and therapeutic inertia during primary care visits among older adults with hypertension?
In older adults with hypertension, higher questionnaire-assessed fall risk is associated with 30% higher odds of clinician therapeutic inertia when blood pressure is uncontrolled, despite being associated with slightly lower odds of uncontrolled blood pressure overall.
May increase therapeutic inertia in high fall-risk older adults with uncontrolled BP; hypothesis-generating and should not yet change practice.
Therapeutic inertia (TI), or failure to escalate or initiate BP lowering medications when BP is uncontrolled, increases with advancing age and may in part be due to perceived fall risk. This study examined the association of a fall risk assessment, based on patient response to three questions administered by trained staff, with uncontrolled BP (≥140/90 mmHg) during a clinic visit and with TI during clinic visits with uncontrolled BP among 13 893 patients age ≥ 65 years corresponding to 41 122 primary care visits. Separate generalized linear mixed effects models were used to examine the association of fall risk (low, moderate, and high) with uncontrolled BP and with TI at a clinic visit after adjustment for demographics, comorbidities, and total number of visits. Baseline mean age was 73.0 years (standard deviation [SD] 5.6), 43.3% were men and questionnaire-assessed fall risk severity was low in 73.6%, moderate in 14.3%, and high in 12.2%. Compared to low fall risk, the adjusted odds of uncontrolled BP during a clinic visit were 0.97 (95% CI: 0.89, 1.06) and 0.90 (95% CI: 0.82, 0.98) with moderate and high fall risk, respectively. In contrast, adjusted odds of TI during a clinic visit with BP ≥ 140/90 mmHg was 1.16 (95% CI: 1.01, 1.34) and 1.30 (95% CI: 1.11, 1.52) with moderate and high fall risk, respectively, compared to low fall risk. These findings suggest that perceived fall risk severity may be one of several factors that influence hypertension management in older adults.
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Hiura et al. (2024) conducted a cohort in Hypertension in older adults (n=13,893). High questionnaire-assessed fall risk (≥2 'Yes' responses on 3-item STEADI-based survey) vs. Low questionnaire-assessed fall risk (0 'Yes' responses) was evaluated on Therapeutic inertia (failure to initiate or escalate BP-lowering medications) during a primary care clinic visit with uncontrolled blood pressure (≥140/90 mmHg) (OR 1.30, 95% CI 1.11, 1.52). High questionnaire-assessed fall risk was associated with increased odds of therapeutic inertia during visits with uncontrolled BP (adjusted OR 1.30, 95% CI 1.11-1.52) compared to low fall risk.
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