Key result
Endomyocardial fibrosis, characterized by endocardial plaques and calcification, is associated with ischemic episodes and arrhythmogenic potentials across various age groups.
Case Report (n=15)
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Highlights the association between endomyocardial fibrosis and coronary artery disease with arrhythmogenic potential in tropical regions.
Aim: To analyse the increasing burden of coronary artery disease (CAD) in tropical and subtropical belts of the Equator since it remains blurred and carries a grim prognosis. Introduction: Endomyocardial fibrosis [EMF] is a tropical febrile disorder, confined to peculiar and limited geographical areas. Plaque buildup in endocardium and coronary arteries, causing ischemic injury and arrhythmic episodes, is a vanishing mystery in its pathogenesis and emphasizing alternative routes for understanding and treatment of this enigmatic disease. Case Report: 15 cases in various age groups were reported with potential complications of coronary artery disease and arrhythmias, associated with endocardial lesions, the characteristic feature of endomyocardial fibrosis. Conclusion: The narrowing of coronary arteries as a result of thickening of the walls, spasm, inflammation, plaques and its rupture produce ischemic episodes which can occur slowly or suddenly in a devastating pattern with arrhythmogenic potentials. The important steps to prevent and decrease the risk of CAD is to reduce the chance of getting this disorder by epidemiological measures with an advice of blood thinning medications such as small daily dose aspirin, antibiotics in susceptible individuals and revascularization in established myocardial infarction.
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Ramachandran Muthiah (2018) conducted a case report in Coronary artery disease and arrhythmias associated with endomyocardial fibrosis (n=15). Endomyocardial fibrosis was evaluated. Endomyocardial fibrosis, characterized by endocardial plaques and calcification, is associated with ischemic episodes and arrhythmogenic potentials across various age groups.
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