Key result
Mind wandering significantly modulated the relationship between physical activity and resting-state hippocampal functional connectivity, showing divergent connectivity patterns in high versus low mind wandering groups.
Why the study?
Physical activity affects cognitive and brain function with interindividual variability, prompting evaluation of whether mind wandering modulates relations between physical activity and resting-state hippocampal functional connectivity.
Cross-Sectional (n=99)
No
p-value: p=<0.001
The relationship between physical activity and hippocampal functional connectivity varies depending on an individual's level of mind wandering.
Mind wandering may moderate physical activity-hippocampal connectivity links; leaves open mechanisms for targeted trials.
Physical activity is critical for maintaining cognitive and brain health. Previous studies have indicated that the effect of physical activity on cognitive and brain function varies between individuals. The present study aimed to examine whether mind wandering modulated the relations between physical activity and resting-state hippocampal functional connectivity. A total of 99 healthy adults participated in neuroimaging data collection as well as reported their physical activity in the past week and their propensity to mind wandering during typical activities. The results indicated that mind wandering was negatively related to the resting-state functional connectivity between hippocampus and right inferior occipital gyrus. Additionally, for participants with higher level of mind wandering, physical activity was negatively related to hippocampal connectivity at left precuneus and right precentral gyrus. In contrast, such relations were positive at right medial frontal gyrus and bilateral precentral gyrus for participants with lower level of mind wandering. Altogether, these findings indicated that the relations between physical activity and hippocampal functional connectivity vary as a function of mind wandering level, suggesting that individual differences are important to consider when we aim to maintain or improve cognitive and brain health through increasing physical activity.
No takes yet. Share an insight, caveat, or question.
Shi et al. (2022) conducted a cross-sectional in Healthy (n=99). Physical activity and mind wandering was evaluated on Resting-state functional connectivity between the hippocampus and other brain regions (p=<0.001). Mind wandering significantly modulated the relationship between physical activity and resting-state hippocampal functional connectivity, showing divergent connectivity patterns in high versus low mind wandering groups.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: