Key result
Pregnancy increases the risk of acute myocardial infarction up to 3-4 fold, and primary percutaneous coronary intervention is considered the optimal medical management.
Although rare, pregnancy-related acute myocardial infarction carries high maternal and fetal mortality, requiring a multidisciplinary approach where primary PCI is considered the optimal medical management.
Supports primary PCI for pregnancy-related MI; leaves open need for dedicated RCTs to guide practice.
The prevalence of cardiac disease in pregnancy is about 0.4-4% based on various study (1-3). Although heart disease and thromboembolism are one of the leading causes (about 32%) of maternal death in pregnancy (4), ischemic heart disease (IHD) and myocardial infarction (MI) are uncommon in pregnancy with a rate less than 1/10000 deliveries in western countries (4-9). Studies showed that pregnancy increases the risk of acute myocardial infarction (AMI) up to 3-4 fold compared with nonpregnant reproductive-age women (2,4,5,10) and have poor maternal and fetal outcome Maternal mortality rate is about 5-37% and is twice higher with AMI in peripartum in comparison with mortality in antepartum and postpartum Fetal mortality is mainly associated with maternal mortality and is about 9-34%. Maternal survival is associated with good fetal prognosis The aim of this study is to collect and review the new data on the diagnosis and management of acute MI in pregnancy from numerous articles published since 2000.
No takes yet. Share an insight, caveat, or question.
Sadeghi et al. (2014) conducted a review in Pregnancy-Related Acute Myocardial Infarction. Medical and surgical management (including PCI and CABG) was evaluated. Pregnancy increases the risk of acute myocardial infarction up to 3-4 fold, and primary percutaneous coronary intervention is considered the optimal medical management.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: