Key result
Abnormal uterine artery Doppler (pulsatility index >1.5) at 18-20 weeks of gestation was associated with a four-fold higher incidence of adverse pregnancy outcomes in low-risk women (80.28% vs 18.59%, p<0.001).
Why the study?
Does abnormal uterine artery Doppler (pulsatility index > 1.5) predict adverse pregnancy outcomes in pregnant women at 18-20 weeks gestation?
Population
343 pregnant women between 18-20 weeks of gestation with viable pregnancy, mean age 28.63 years, 57.43%…
Comparison
Abnormal bilateral uterine artery Doppler… vs Normal uterine artery Doppler.
Design
Cohort, Clinicians managing the pregnancy were blinded to the ultrasound…
Follow-up
until the end of pregnancy
Authors
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Hypothesis-generating for uterine artery Doppler in low-risk pregnancies; prospective validation required before practice change.
Observational (n=343)
Single-blind
Does abnormal uterine artery Doppler (pulsatility index > 1.5) predict adverse pregnancy outcomes in pregnant women at 18-20 weeks gestation?
Effect estimate: four fold higher incidence
Absolute Event Rate: 80.28% vs 18.59%
p-value: p=<0.001
Second-trimester uterine artery Doppler showing unilaterally increased pulsatility index is a useful screening tool for predicting adverse pregnancy outcomes in both high- and low-risk women.
Adiga et al. (2018) conducted an observational in Pregnancy (n=343). Abnormal uterine artery Doppler (Pulsatility Index > 1.5) vs. Normal uterine artery Doppler (Pulsatility Index < 1.5) was evaluated on Adverse pregnancy outcome in low-risk pregnancies (four fold higher incidence, p=<0.001). Abnormal uterine artery Doppler (pulsatility index >1.5) at 18-20 weeks of gestation was associated with a four-fold higher incidence of adverse pregnancy outcomes in low-risk women (80.28% vs 18.59%, p<0.001).
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