The treatment of depression with desoxyephedrine (pervitin or methedrine) is not new. In 1943 Davidoff reported a comparison of the effect of this preparation with amphetamine and dextroamphetamine on 8 normal and 8 depressed individuals. He found that desoxyephedrine gave the most rapid results, acted the longest and produced the greatest motor activity the most often.
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Goražd Rudolf (1949) studied this question.
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