Key result
Acute myocardial infarction can act as a triggering factor for the manifestation of secondary Takotsubo cardiomyopathy, likely due to ischemia-induced catecholamine release.
Case Report (n=2)
No
This case series suggests that acute myocardial infarction can act as a triggering factor for Takotsubo cardiomyopathy.
AMI may trigger secondary Takotsubo; hypothesis-generating observation requiring prospective confirmation before clinical consideration.
Takotsubo cardiomyopathy (TCM) is a well-known complication of many conditions associated with emotional or physical stress. Abnormal catecholamine release has been hypothesized to be the main cause of TCM. Myocardial infarction (MI) is associated with release of large amounts of catecholamines. We present here two cases in which patients simultaneously suffered from acute MI and TCM. In these elderly women without prior history of severe somatic diseases we have not revealed any external stressing factor responsible for the initiation of the disease. Therefore, we have considered primary coronary event (acute MI) to be a triggering factor of TCM manifestation.
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Muksinova et al. (2017) conducted a case report in Takotsubo cardiomyopathy and acute myocardial infarction (n=2). Acute myocardial infarction was evaluated. Acute myocardial infarction can act as a triggering factor for the manifestation of secondary Takotsubo cardiomyopathy, likely due to ischemia-induced catecholamine release.
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