Key result
ABO blood group system had no significant effect on cardiac autonomic function, with no alterations observed in parasympathetic or sympathetic responses among healthy young adults.
Why the study?
ABO blood group is associated with cardiovascular disease and abnormal autonomic response contributes to cardiac morbidity, but data on the association between blood groups and cardiac autonomic function are lacking.
Does ABO blood group affect cardiac autonomic function in healthy young adults?
Cross-Sectional (n=150)
No
Does ABO blood group affect cardiac autonomic function in healthy young adults?
ABO blood group does not appear to significantly influence cardiac autonomic function responses to physiological stressors in healthy young adults.
Does not support incorporating ABO into autonomic assessments; leaves open effects in older or diseased populations.
Background: ABO blood group has been associated with various disease phenotypes, particularly cardiovascular disease. Abnormal autonomic response also plays a role in cardiac morbidity. Increasing attention is being focused on the role of autonomic nervous system in health and disease. The literature lacks data on the association of blood groups and cardiac autonomic function. The aim of the study was to find out the association between different blood groups and cardiovascular autonomic functions in young adults.Methods: 150 healthy young students of MMU aged 18-25 years, divided into four groups based on ABO blood grouping, determined by agglutination test (group A, group B, group O and group AB). Various autonomic function tests done were lying to standing test, Valsalva maneuver, Hand grip test (HGT) and Cold pressor test (CPT).Results: The mean baseline heart rate was significantly higher in group O as compared to group A. No parasympathetic alteration between different ABO blood groups was seen. Blood pressure response to HGT and CPT was not statistically significant between different blood groups.Conclusions: Present study revealed no alteration in cardiac autonomic function with regards to ABO blood grouping in young adults.
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Rafiq et al. (2019) conducted a cross-sectional in Healthy (n=150). ABO blood group vs. Other ABO blood groups was evaluated on Cardiac autonomic function (parasympathetic and sympathetic responses) (p=>0.05). ABO blood group system had no significant effect on cardiac autonomic function, with no alterations observed in parasympathetic or sympathetic responses among healthy young adults.
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